Results 51 to 60 of about 39,749,831 (352)

Circos: an information aesthetic for comparative genomics.

open access: yesGenome Research, 2009
We created a visualization tool called Circos to facilitate the identification and analysis of similarities and differences arising from comparisons of genomes.
M. Krzywinski   +7 more
semanticscholar   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Acknowledgement to Reviewers of Information in 2014

open access: yesInformation, 2015
The editors of Information would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2014:[...]
Information Editorial Office
doaj   +1 more source

DIDET: Digital libraries for distributed, innovative design education and teamwork. Final project report [PDF]

open access: yes, 2008
The central goal of the DIDET Project was to enhance student learning opportunities by enabling them to partake in global, team based design engineering projects, in which they directly experience different cultural contexts and access a variety of ...
Breslin, C.   +2 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Acknowledgement to Reviewers of Information in 2017

open access: yesInformation, 2018
Peer review is an essential part in the publication process, ensuring that Information maintains high quality standards for its published papers. In 2017, a total of 153 papers were published in the journal.[...]
Information Editorial Office
doaj   +1 more source

Managing contextual information in semantically-driven temporal information systems [PDF]

open access: yes, 2011
Context-aware (CA) systems have demonstrated the provision of a robust solution for personalized information delivery in the current content-rich and dynamic information age we live in.
Isiaq, SO, Osman, T, Peytchev, E
core   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

Information, information processing and gravity

open access: yes, 2007
I discuss fundamental limits placed on information and information processing by gravity. Such limits arise because both information and its processing require energy, while gravitational collapse (formation of a horizon or black hole) restricts the ...
Lloyd S.   +4 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

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