Results 91 to 100 of about 2,194,214 (308)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Why do borrowers pledge collateral? new empirical evidence on the role of asymmetric information [PDF]

An important theoretical literature motivates collateral as a mechanism that mitigates adverse selection, credit rationing, and other inefficiencies that arise when borrowers hold ex ante private information.
Allen N. Berger, Marco A. Espinosa-Vega, Nathan H. Miller, W. Scott Frame   +3 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Tariffs and the Adoption of Clean Technology Under Asymmetric Information [PDF]

This paper examines the effect of import tariffs on the decision of a foreign monopolist to adopt “clean” technology – technology that reduces the flow of a negative cross-border externality per unit of exports.
Rodney Ludema, Taizo Takeno
core  

Electronic Health Records: An International Perspective on "Meaningful Use" [PDF]

, 2011
Examines the extent of meaningful use of electronic health records in Denmark, New Zealand, and Sweden, including sharing information with organizations, health authorities, and patients.
Bradford H. Gray, Ib Johansen, Sabine Koch, Tom Bowden   +3 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

ASSESSMENT OF INFORMATION TECHNOLOGY ADOPTION IN PROJECT INFORMATION EXCHANGE IN NIGERIAN CONSTRUCTION INDUSTRY

Arid Zone Journal of Engineering, Technology and Environment, 2019
Information Technology (IT) has been applied by various industries with significant improvement in the practice and strategic standing of the industries.
Y. U. Datti, A. Dahiru, O. Olamilokun
doaj   +2 more sources

Information technology adoption in Indonesia’s small-scale dairy farms

Open Agriculture
The use of modern digital technologies contributes to small-scale dairy farmers enhancing their business processes, increasing productivity, and addressing challenges related to sustainability.
Indriasari Sofiyanti, Sensuse Dana Indra, Resti Yuni   +2 more
doaj   +1 more source

INFORMATION AND THE ADOPTION OF PRECISION FARMING [PDF]

This study examines the relationship between precision farming information sources and precision farming adoption. The analysis accounts for the fact that not all farmers are aware of precision farming techniques and that those who are aware may not be a
Daberkow, Stan G., McBride, William D.
core   +1 more source

A strategic framework for e-government adoption in public sector organisations [PDF]

, 2004
E-government has been recognized as a change agent for public sector reform. Through this change, the public sector organisation plans to increase operating efficiencies, build information-sharing partnerships and improve communication with other ...
Alshawi, S, Ebrahim, ZA, Irani, Z
core   +1 more source