Results 241 to 250 of about 2,394,675 (300)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Visual analytics framework for survival analysis and biomarker discovery from gene expression data. [PDF]

PLoS One
Kokošar J, Turkay C, Ausec L, Štajdohar M, Zupan B.   +4 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Tumor Genomics and Liquid Biopsy in Cancer Biology: From Static Snapshots to Dynamic Measurements. [PDF]

Biomolecules
Urbini M.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Women's Autonomy in Obstetric Care: A Qualitative Study on Violations and Experiences. [PDF]

Nurs Health Sci
Perelló-Iñiguez C, García-Garro V, Mena-Tudela D, Biurrun-Garrido A.   +3 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Optimizing healthcare through alignment and nurturing across cultures (OHANA). [PDF]

MethodsX
Pistacchio C, Napolitano D, Figura M, Amato S, Lo Cascio A, Ribaudi E, Giannetta N, Carrodano S, Arcadi P, Stievano A.   +9 more
europepmc   +1 more source

Research priorities for improved pandemic and epidemic intelligence.

Lancet Glob Health
Tornimbene B, Redies I, AbdelMalik P, Abernethy J, Anton N, Awofisayo-Okuyelu AA, Fitzner J, Franz C, Ghozzi S, Golding J, Haouala A, Hersey S, Imai-Eaton N, Kampmann B, Krause G, Lais RS, de Waroux OLP, Carrera RM, Ngamala PN, Norton A, Ross AL, Sangameshwaran R, Van der Zee M, Wymer E, Morgan O.   +24 more
europepmc   +1 more source