Results 41 to 50 of about 733,650 (284)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
The research applies the generation matters of the geoinformational system for regional resources monitoring and management decision information-analytical support. The article represents the system structure, its functions, monitoring data configuration
И. В. Шишко +5 more
doaj +1 more source
A Decision Support Model for the Selection of Best Value Information Technology Procurement Method [PDF]
SUMMARY: The procurement of Information Technology (IT) is as important as the use of the technology. Procurement includes two aspects: the selection of the right IT product as well as the selection of the method to procure it.
Perera, Srinath (R18622) +2 more
core
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Searching is something we do everyday both in digital and physical environments. Whether we are searching for books in a library or information on the web, search is becoming increasingly important.
Wilson, Max L. +2 more
core +1 more source
The actuality of the paper is due to the intensification of the strategic, geopolitical, economic, ecological and other challenges to the Russian Arctic’ industrial development which requires the State to respond to them.
E. L. Moreva, L. V. Obolenskaya
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Inclusive education: information and analytical support
Інклюзивна освіта потребує постійно оновлюваного інформаційно-аналітичного супроводу щодо: організації інклюзивної освіти, вирішення актуальних завдань освітньої інклюзії, моніторингу якості освіти та системного аналізу потреб дітей з ООП, адаптації освітніх процесів та оцінюванню ефективності впроваджених програм, підготовки педагогів до роботи в ...
openaire +3 more sources

