Results 101 to 110 of about 1,405,618 (304)
Non-Equilibrium Social Science and Policy: Introduction and Essays on New and Changing Paradigms in Socio-Economic Thinking [PDF]
, 2017 The overall aim of this book, an outcome of the European FP7 FET Open NESS project, is to contribute to the ongoing effort to put the quantitative social sciences on a proper footing for the 21st century. A key focus is economics, and its implications on
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
AI based multiomics integration for cancer diagnosis and prognosis
Journal of Genetic Engineering and BiotechnologyCancer remains a critical global health challenge, driving the need for innovative approaches in diagnosis and treatment. This research introduces OmicsFusionNet, an AI-powered hybrid model integrating machine learning and deep learning to revolutionize ...
Moshira Ghaleb +3 more
doaj +1 more source
Bayesian Research at the NASA Ames Research Center,Computational Sciences Division [PDF]
, 2003 NASA Ames Research Center is one of NASA s oldest centers, having started out as part of the National Advisory Committee on Aeronautics, (NACA). The site, about 40 miles south of San Francisco, still houses many wind tunnels and other aviation related ...
Morris, Robin D.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
An Introduction to Programming for Bioscientists: A Python-based Primer
, 2016 Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in the biosciences utilizes computer programs.
Ekmekci, Berk +2 more
core +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Programming Environment Evaluation Methodology for Object-Oriented Systems [PDF]
The object-oriented design strategy as both a problem decomposition and system development paradigm has made impressive inroads into the various areas of the computing sciences.
Dominick, Wayne D., Moreau, Dennis R.
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Architecture of Environmental Risk Modelling: for a faster and more robust response to natural disasters [PDF]
, 2014 Demands on the disaster response capacity of the European Union are likely to increase, as the impacts of disasters continue to grow both in size and frequency.
de Rigo, Daniele +2 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source