Results 81 to 90 of about 1,405,618 (304)

Blockchain-Based Model to Predict Agile Software Estimation Using Machine Learning Techniques

open access: yesIET Software
The importance of software estimation is utmost, as it is one of the most crucial activities for software project management. Although numerous software estimation techniques exist, the accuracy achieved by these techniques is questionable.
Mohammad Ayub Latif   +5 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

NISS WebSwap: A Web Service for Data Swapping [PDF]

open access: yes
Data swapping is a statistical disclosure limitation practice that alters records in the data to be released by switching values of attributes across pairs of records in a fraction of the original data.
Alan F. Karr   +2 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Static and Dynamic Aspects of Application Domains: An Inductively Defined Modeling Technique That Allows Decomposition

open access: yesComplex Systems Informatics and Modeling Quarterly, 2016
Modeling is one of the most important parts of requirements engineering. Most modeling techniques focus primarily on their pragmatics and pay less attention to their syntax and semantics.
Theo van der Weide   +2 more
doaj   +1 more source

Supporting Regularized Logistic Regression Privately and Efficiently

open access: yes, 2015
As one of the most popular statistical and machine learning models, logistic regression with regularization has found wide adoption in biomedicine, social sciences, information technology, and so on.
Li, Wenfa   +3 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Inferring directional relationships in microbial communities using signed Bayesian networks

open access: yesBMC Genomics, 2020
Background Microbe-microbe and host-microbe interactions in a microbiome play a vital role in both health and disease. However, the structure of the microbial community and the colonization patterns are highly complex to infer even under controlled wet ...
Musfiqur Sazal   +4 more
doaj   +1 more source

Informatics and Natural Computation: Final Report [PDF]

open access: yes, 2010
The purpose of this grant is to develop an interdisciplinary course in Informatics and Natural Computation that would service undergraduate computer, natural, and physical science majors.
Marchese, Francis T.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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