Results 61 to 70 of about 711,546 (282)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Performance Evaluation of Medical Records Department with Balanced Scorecard approach in Fatemehzahra Hospital of Najafabad, Iran

مدیریت اطلاعات سلامت, 2010
Introduction: Medical Records Department (MRD) is an important source for evaluating and planning of care services. The main goal of this research was performance evaluation of medical records department with Balanced Scorecard (BSC) approach in a ...
Sima Ajami, Shahram Tofighi, Nahid Tavakoli, Afsaneh Ebadsichani   +3 more
doaj  

Exploring the cost implications of different treatment modalities for uterine fibroids under the DRG system

Frontiers in Public Health
This paper, based on data from inpatient medical records with uterine fibroids (ICD-10: D25) from the medical record homepages of secondary and higher-level hospitals in Sichuan Province between 2016 and 2024, investigated differences in medical resource
Kun Tan, Linya Huang, Yuxian Nie, Qiuling Shi, Qiushuo Liu, Su Yan, Ting Lu, Xite Yang, Yongzeng Lai, Xiaofeng Zhu   +9 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Managing records as reliable evidence for ICT/ e-Government and freedom of information : Kenya court case study [PDF]

, 2011
This case study was undertaken at the Kenyan Court of Appeal, to examine the manner in which the courts are handling records management in the electronic environment.
International Records Management Trust
core   +1 more source

مقایسه وضعیت مدیریت داده های کارازمایی بالینی دارویی با استانداردهای مدیریت مطلوب داده های بالینی در مراکز تحقیقاتی درمانی دانشگاه علوم پزشکی تهران سال 90

مدیریت اطلاعات سلامت, 2013
مقدمه: اجراي مديريت مطلوب داده‌ها، براي هر کارآزمايي باليني ضروري است. با اين حال ممکن است اين مسأله در طول مراحل برنامه‌ريزي و اجراي کارآزمايي باليني ناديده گرفته و مورد غفلت واقع شود. هدف از انجام این مطالعه، شناسایی وضعیت مديريت داده‌هاي کارآزمايي‌هاي
Farahnaz Sadoughi, Masoud Salehi, Leila Amirhajlou   +2 more
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Non-Clinical Quality of Care in Teaching Hospitals: Responsiveness Level and Relative Importance of Different Domains

پیاورد سلامت, 2017
Background and Aim: Considering the scope of tasks and the role of teaching hospitals in the promotion of population health, it is important to consider their responsiveness as one of the three goals of health system.
Somayeh Fazaeli, Mehdi Yousefi, Zahra Sadat Ershadnia   +2 more
doaj  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source