Results 61 to 70 of about 2,246,609 (297)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Examining Racial Disparities in Criminal Case Outcomes among Indigent Defendants in San Francisco [PDF]

, 2017
We reviewed 10,753 complete case records, consisting of cases between 2011 and 2014, from the San Francisco Public Defender's Office. These data were stored in the Public Defender's GIDEON case management system, which draws from data maintained by the ...
Bernardo Santos Da Silveria, Emily Owens, Erin M. Kerrison   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Better duplicate detection for systematic reviewers: Evaluation of Systematic Review Assistant-Deduplication Module [PDF]

, 2015
BACKGROUND: A major problem arising from searching across bibliographic databases is the retrieval of duplicate citations. Removing such duplicates is an essential task to ensure systematic reviewers do not waste time screening the same citation multiple
Carter, Matt, Glasziou, Paul, Hoffmann, Tammy, Rathbone, John   +3 more
core   +1 more source

Information security and records management

Journal of Information Processing and Management, 2006
通常，情報セキュリティはITや情報システムのサイドから論じられる。しかし，これでは技術的な側面は解決しても，ほとんどの情報は文書・記録の形式になっているために，情報の中身に即したセキュリティ対策は進まない。情報セキュリティの3要素である機密性・完全性・可用性を維持し，情報を保護するためには，文書・記録管理のサイドからのアプローチがどうしても欠かせない。これからは単なるITセキュリティではなく，コンプライアンス，リスク・マネジメントに対応した文書・記録情報のセキュリティを考える時代である。
openaire   +2 more sources

Readiness of Hospitals with Quality Management Systems Based on Joint Commission on Accreditation Standards

مدیریت اطلاعات سلامت, 2012
Introduction: Recently, the accreditation program has been used increasingly by an emphasis on patient safety. In Iran, efforts have been made to establish the accreditation program.
Shirin Abbasi, Nahid Tavakoli, Mohammad Moslehi   +2 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Performance Evaluation of Medical Records Department with Balanced Scorecard approach in Fatemehzahra Hospital of Najafabad, Iran

مدیریت اطلاعات سلامت, 2010
Introduction: Medical Records Department (MRD) is an important source for evaluating and planning of care services. The main goal of this research was performance evaluation of medical records department with Balanced Scorecard (BSC) approach in a ...
Sima Ajami, Shahram Tofighi, Nahid Tavakoli, Afsaneh Ebadsichani   +3 more
doaj  

Exploring the cost implications of different treatment modalities for uterine fibroids under the DRG system

Frontiers in Public Health
This paper, based on data from inpatient medical records with uterine fibroids (ICD-10: D25) from the medical record homepages of secondary and higher-level hospitals in Sichuan Province between 2016 and 2024, investigated differences in medical resource
Kun Tan, Linya Huang, Yuxian Nie, Qiuling Shi, Qiushuo Liu, Su Yan, Ting Lu, Xite Yang, Yongzeng Lai, Xiaofeng Zhu   +9 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source