Results 91 to 100 of about 1,859,644 (362)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Temperature-density dependent hidden order of amorphous carbon
Communications PhysicsThe microscopic structure of amorphous carbon is inherently complex, and its underlying topological order remains poorly understood. Here, we developed a high-precision machine learning potential and performed large-scale molecular dynamics simulations ...
Yutao Liu +6 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Role of Integration in Health-Based Information Infrastructures [PDF]
, 2010 Gunnar Ellingsen, Kristoffer Røed
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Lunar chart. Lac 93, Mare Humorum /
, 1962 1st ed., June 1962. Map of the moons surface showing the lunar mare named Mare Humorum. Relief shown pictorially by spot heights.; "This chart was prepared with advisory assistance from Dr. Gerard P. Kuiper and his collaborators, D.W.G.
Aeronautical Chart and Information Center (U.S.)
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
New Britain, provisional map [cartographic material] /
, 1943 Various ed. Topographic map series of New Britain, Umboi and Tolokiwa islands, showing transportation, trails, water features, plantation, vegetation and native villages.
United States. Army. South West Pacific Area. Base Map Plant.
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