Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A Behavioral Study of the Normative of the Listed Company Information Disclosure after IPO
, 2014 Shuxin Cao, Jianqiong Wang
openalex +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Actual and Perceived Knowledge about COVID-19: The Role of Information Behavior in Media
, 2020 Granderath JS +3 more
europepmc +1 more source
Internet's Effect on Information Seek-ing Behavior of Medical Professionals in Uttarakhand: A Study
Dr. Vinod Kumar
openalex +1 more source
Information Exchange and Behavior
, 2009 This dissertation studies the behavioral characteristics of participants engaged in information exchange in the context of online communities. Online communities are defined as collectives of individuals that use computer mediated communication to facilitate interaction over a shared purpose and/or objective.
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Patient information leaflets: informing or frightening? A focus group study exploring patients’ emotional reactions and subsequent behavior towards package leaflets of commonly prescribed medications in family practices [PDF]
, 2014 Oliver Rudolf Herber +4 more
openalex +1 more source