Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Introduction. This paper explores the notion and use of third space as conceptualised by Kuhlthau, Maniotes and Caspari on guided inquiry in information literacy and in human computer interaction literature.
Meyer, Anika +2 more
core
A Qualitative Evaluation of Eat, Learn, Grow: A Digital Microlearning Programme to Promote Responsive Feeding Practices. [PDF]
Baxter KA, So JTH, Gallegos D, Byrne R.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Parental body mass index and offspring childhood body size and eating behaviour: A structural equation modelling analysis in the Norwegian Mother, Father and Child Cohort Study. [PDF]
Bond TA +11 more
europepmc +1 more source
Subject positions of children in information behaviour research.
Introduction: This paper problematises how children are categorised as a specific user group within information behaviour research and discusses the implications of this categorisation. Methods: Two edited collections of papers on children’s information behaviour are analysed.
openaire +2 more sources
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Examining the 'Consumer Repair Journey' and Business Intervention Opportunities to Enhance Customer Experience and Satisfaction. [PDF]
Dao T, Cooper T, Watkins M.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Context-Awareness and Biologically Inspired Behaviour Based on Attention Mechanisms for Natural Human-Robot Interaction. [PDF]
García-Martínez J +4 more
europepmc +1 more source

