Results 61 to 70 of about 15,718,666 (366)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Detection and attribution of climate extremes in the observed record

Weather and Climate Extremes, 2016
We present an overview of practices and challenges related to the detection and attribution of observed changes in climate extremes. Detection is the identification of a statistically significant change in the extreme values of a climate variable over ...
David R. Easterling, Kenneth E. Kunkel, Michael F. Wehner, Liqiang Sun   +3 more
doaj   +1 more source

Enhancing the Capacity of Community Health Centers to Achieve High Performance [PDF]

, 2010
Based on a survey of community health centers, assesses access to care, care coordination, quality improvement efforts, health information technology adoption, and ability to serve as patient-centered medical homes.
Anne C. Beal, Kristof Stremikis, Melinda K. Abrams, Michelle M. Doty, Susan E. Hernandez   +4 more
core  

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

AMOC and North Atlantic Ocean Decadal Variability: A Review

Oceans
The North Atlantic Ocean is vital to Earth’s climate system. Scientific investigations have identified the Atlantic Meridional Overturning Circulation (AMOC) as a significant factor influencing global climate change.
Dan Seidov, Alexey Mishonov, James Reagan   +2 more
doaj   +1 more source

Information Governance in the Scientific Centers [PDF]

حکمرانی و توسعه
Information governance is an approach to managing the acquisition, creation, storage, organizing, sharing, dissemination and effective use of information inside and outside an organization that most organizations today use to facilitate and expedite the ...
Ali Sharafi
doaj   +1 more source

Production of oriented nitrogen-vacancy color centers in synthetic diamond

, 2011
The negatively charged nitrogen-vacancy (NV-) center in diamond is an attractive candidate for applications that range from magnetometry to quantum information processing. Here we show that only a fraction of the nitrogen (typically < 0.5 %) incorporated
Beausoleil, R. G., Cruddace, R. J., D’Haenens-Johansson, U. F. S., Edmonds, A. M., Fu, K.-M. C., Markham, M. L., Newton, Mark E., Santori, C., Twitchen, D. J.   +8 more
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Strategic-decision quality in public organizations : an information processing perspective [PDF]

, 2018
This study draws on information processing theory to investigate predictors of strategic-decision quality in public organizations. Information processing theory argues that (a) rational planning practices contribute to strategic-decision quality by ...
Desmidt, Sebastian, George, Bert
core   +1 more source