Results 91 to 100 of about 7,190 (304)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Gain-aware caching scheme for information-centric networking
The in-network caching system of information-centric networking had to deal with the popularity of huge number of content chunks and make efficient usage of storage resources.A content popularity based caching gain opti-mization model aimed to get ...
Long CHEN +4 more
doaj +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Efficient Coded-Block Delivery and Caching in Information-Centric Networking
Information-centric networking (ICN) provides request aggregation and caching strategies that can improve network performance by reducing content server loads and network traffic.
Yan Liu +5 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Information-Centric Networking in Mobile and Opportunistic Networks
Information Centric Networking (ICN) as an emerging paradigm for the Future Internet has initially been rather focusing on bandwidth savings in wired networks, but there might also be some significant potential to support communication in mobile wireless
Vasilios A. Siris +5 more
core +1 more source
T-Move: A Light-Weight Protocol for Improved QoS in Content-Centric Networks with Producer Mobility
Recent interest in applications where content is of primary interest has triggered the exploration of a variety of protocols and algorithms. For such networks that are information-centric, architectures such as the Content-Centric Networking have been ...
Swaroopa Korla, Shanti Chilukuri
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Challenge and Implementation of Content-Centric Networking
CCN is communication architecture that takes content as a primitive,and retrieves content by name,not by host IP again.It builds on publish/subscribe and network-embedded caching with bandwidth-storage tradeoff.Since it is a clean-slate design,there are ...
Xinggong Zhang, Tong Niu, Zongming Guo
doaj +2 more sources
Design and Evaluation of Probabilistic Caching in Information-Centric Networking
In-network caching is a key feature of information-centric networking (ICN). However, challenges still exist in ICN caching such as how to place content replicas among cache nodes to maximize cache system benefits without introducing too much overhead ...
Haibo Wu +4 more
doaj +1 more source

