Results 41 to 50 of about 839,113 (264)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Survey on medical waste disposal in medical and healthcare institutions in Hefei City

Shanghai yufang yixue
ObjectiveTo investigate the production, disposal, and disinfection management of medical waste in medical and healthcare institutions in Hefei City, so as to provide a basis for further improving the disposal work of medical waste in the city's medical ...
WANG Jiao, GONG Chun, LIANG Yunfeng
doaj   +1 more source

Predictive Accuracy of Logit Regression for Data-Scarce Developing Markets: A Nigeria and South Africa Study

Engineering Proceedings, 2023
This research examines how much forecasting accuracy can be achieved by modelling the relationships between listed real estate and macroeconomic time series variables using the logit regression model.
Jonathan D. Oladeji, Benita G. Zulch, Joseph A. Yacim   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Application of big data technology in emergency management platform informatization construction

Open Computer Science
The emergence of emergencies has impacted China’s politics, economy, and other aspects to varying degrees, seriously threatening social stability, economic development, and people’s happiness.
Lin Meirong
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Research on the prediction method of debris flow susceptibility based on PSO-LSTM-SAM [PDF]

E3S Web of Conferences
To mitigate the losses caused by debris flow disasters, effective prediction methods are essential. However, traditional approaches often suffer from low accuracy and poor generalization in predicting debris flow events.
Han Zhaoliang, Li Xiang, Li Bo, Wu Kun, He Zhongquan, Hua Zexi   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Research on Transfer Learning-Based Fault Diagnosis for Planetary Gearboxes Under Cross-Operating Conditions via IDANN

Information
To address the limited performance of transfer fault diagnosis for planetary gearboxes under cross-operating conditions, which is caused by the heterogeneous feature distribution of vibration data and insufficient feature extraction.
Xiaolu Wang, Aiguo Wang, Haoyu Sun, Xin Xia   +3 more
doaj   +1 more source