Results 71 to 80 of about 21,204,927 (295)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Discover Applied SciencesSmart campus infrastructure (SCI) is highly dependent on Internet of Things sensing devices, building automation system and campus private network. Once there is a fault in the operation process, it will often lead to teaching interruption, energy waste ...
Pengyao Shi, Jiaqi Zhai
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Integrating Construction Process Documentation with the use of Building Information Modeling
Budownictwo i Architektura, 2013 This paper presents a practical approach to the problem of data collection using the BIM model. The aim is to show how to use the BIM model to capture the data from the 3D design documentation, construction documents, construction schedule, and the use ...
Krzysztof Zima
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Krapivna. Rehabilitation Attempt
Проект Байкал, 2019 The article describes the peculiarities of rehabilitation of the historical urban environment through the example of Krapivna settlement in the Tula region. The tools for development of the given territory were the benchmark for working on the graduation
Alexei Buinov, Elena Bulgakova
doaj +2 more sources
A lightweight attention-enhanced intrusion detection method for anomalous network traffic analysis
Scientific ReportsNetwork intrusion detection in complex traffic environments requires a careful balance between detection performance and computational efficiency, particularly when models are intended for resource-constrained scenarios.
Xingguo Li +3 more
doaj +1 more source
Exit Statement : 2001-2009 CRC for Construction Innovation [PDF]
, 2009 The Cooperative Research Centre (CRC) for Construction Innovation is Australia’s national centre for research and innovation focused on the needs of the property, design, construction and facility management sectors. The period covered by this report is
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source