Results 191 to 200 of about 3,194,155 (315)

Information content as a health system screening tool for rare diseases. [PDF]

NPJ Digit Med
Groza T, Robinson PN, Lim WK, Narasimhalu K, Hsieh J, Yeo KK, Keow GB, Thomas T, Wong TY, Karnani N, Baynam G, Jamuar SS.   +11 more
europepmc   +1 more source

Covid-19 outbreak and beyond: a retrospect on the information content of short-time workers for GDP now- and forecasting. [PDF]

Swiss J Econ Stat, 2023
Kaufmann S.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Information Content and Maximum Entropy of Compartmental Systems in Equilibrium. [PDF]

Entropy (Basel)
Metzler H, Sierra CA.
europepmc   +1 more source

In Silico Tools to Extract the Drug Design Information Content of Degradation Data: The Case of PROTACs Targeting the Androgen Receptor. [PDF]

Molecules, 2023
Apprato G, D'Agostini G, Rossetti P, Ermondi G, Caron G.   +4 more
europepmc   +1 more source

Information content. [PDF]

Circulation, 1981
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Deep learning-based high-information-content graph representation of early stage bacterial biofilms. [PDF]

NPJ Biofilms Microbiomes
Nersesyan LE, Boiko DA, Kurbanalieva S, Dzhemileva LU, Kozlov KS, Ananikov VP.   +5 more
europepmc   +1 more source

A smartphone-based self-care application for patients with urinary tract stones: identification of information content and functional capabilities. [PDF]

BMC Urol, 2022
Shahmoradi L, Azizpour A, Bejani M, Shadpour P, Rezayi S, Farzi J, Amanollahi A.   +6 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source