Results 91 to 100 of about 831,124 (298)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Values of the Akaike information criterion.
, 2022 Values of the Akaike information criterion of the first 25 models for four volunteers.
Galina Valova (12160766) +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On focussed and less focussed model selection. [PDF]
Model selection usually provides models without specific concern about for which purpose the selected model will be used afterwards. The focussed information criterion, FIC, is developed to select a best model for inference for a given estimand.
Claeskens, Gerda
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Generalized Information-Theoretic Criterion for Multi-Label Feature Selection
IEEE Access, 2019 Multi-label feature selection that identifies important features from the original feature set of multi-labeled datasets has been attracting considerable attention owing to its generality compared to conventional single-label feature selection.
Wangduk Seo, Dae-Won Kim, Jaesung Lee
doaj +1 more source
Empirical Information Criteria for Time Series Forecasting Model Selection [PDF]
In this paper, we propose a new Empirical Information Criterion (EIC) for model selection which penalizes the likelihood of the data by a function of the number of parameters in the model.
R.J. Hyndman, Md B. Billah, A.B. Koehler
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Prediction focussed model selection for autoregressive models. [PDF]
In order to make predictions of future values of a time series, one needs to specify a forecasting model. A popular choice is an autoregressive time series model, where the order of the model is chosen by an information criterion. We propose an extension
Croux, Christophe +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source