Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Note on N in Bayesian Information Criterion for Item Response Models. [PDF]
Appl Psychol Meas, 2018 Cho SJ, De Boeck P.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Bayesian model evidence as a practical alternative to deviance information criterion. [PDF]
R Soc Open Sci, 2018 Pooley CM, Marion G.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Akaike's Bayesian Information Criterion for the Joint Inversion of Terrestrial Water Storage Using GPS Vertical Displacements, GRACE and GLDAS in Southwest China. [PDF]
Entropy (Basel), 2019 Liu Y, Fok HS, Tenzer R, Chen Q, Chen X.
europepmc +1 more source
Ability of the New EU Member States to Fulfill the Exchange Rate Stability Convergence Criterion
This paper assesses exchange rate development and volatility in six new EU member states (Cyprus, Czech Republic, Hungary, Poland, Slovakia, and Slovenia) during the period November 1996 - April 2006.
Stavarek, Daniel
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
A discussion of ‘prior-based Bayesian information criterion’
Statistical Theory and Related Fields, 2019 Jiahua Chen, Zeny Feng
doaj +1 more source
Focused Information Criterion and Model Averaging with Generalized Rank Regression. [PDF]
Stat Probab Lett, 2017 Zhang Q, Duan X, Ma S.
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