Results 111 to 120 of about 15,348,814 (368)
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
Investigating challenges and responses in supply chain management amid unforeseen events
The emergence of increasingly complex global supply networks and the rising risk of unpredictable events may have far-reaching consequences for various industries and the global economy.
Ryciuk Urszula, Zabrocka Agnieszka
doaj +1 more source
On the genericity properties in networked estimation: Topology design and sensor placement
In this paper, we consider networked estimation of linear, discrete-time dynamical systems monitored by a network of agents. In order to minimize the power requirement at the (possibly, battery-operated) agents, we require that the agents can exchange ...
Doostmohammadian, Mohammadreza +1 more
core +1 more source
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Price Discovery Across Geographic Locations in the Foreign Exchange Market [PDF]
The ongoing process of price discovery in foreign exchange markets provides valuable information to certain market participants. Recent empirical findings suggest that aggregate measures of order flow convey information about the fundamental value of the
Chris D'Souza
core
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
About Some Problems of Interdepartmental Interaction when Appointing Socio-Security Payments
Violations of the current legislation on social payments, which have become widespread in recent years, lead to significant budget losses. In part, this is facilitated by the lack of operational interdepartmental interaction of the subject-law ...
M. G. Sedelnikova, A. A. Puzyreva
doaj +1 more source
Information, Capital Gains Taxes & New York Stock Exchange [PDF]
We present evidence regarding the response of stock prices in the New York Stock Exchange to news about capital gains taxes. If information about an upcoming event becomes available, then it should be reflected in prices as soon as the news about it ...
Ferhan Salman
core

