Results 91 to 100 of about 17,789,050 (310)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Information Extraction Framework
The literature provides many techniques to infer rules that can be used to configure web information extractors. Unfortunately, these techniques have been developed independently, which makes it very difficult to compare the results: there is not even a collection of datasets on which these techniques can be assessed. Furthermore, there is not a common
Hassan A. Sleiman, Rafael Corchuelo
openaire +3 more sources
Meta-level Information Extraction [PDF]
This paper presents a novel approach for meta-level information extraction (IE). The common IE process model is extended by utilizing transfer knowledge and meta-features that are created according to already extracted information. We present two real-world case studies demonstrating the applicability and benefit of the approach and directly show how ...
Peter Klügl +2 more
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
BioRAT: extracting biological information from full-length papers [PDF]
Motivation: Converting the vast quantity of free-format text found in journals into a concise, structured format makes the researcher's quest for information easier.
Bernard F. Buxton +16 more
core +2 more sources
Lance A. Ramshaw, Ralph M. Weischedel
+5 more sources
Anthropological, archaeological, and forensic studies situate enforced disappearance as a strategy associated with the Brazilian military dictatorship (1964−1985), leaving hundreds of persons without identity or cause of death identified.
Patricia Martin-Rodilla +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
BlogForever D2.6: Data Extraction Methodology [PDF]
This report outlines an inquiry into the area of web data extraction, conducted within the context of blog preservation. The report reviews theoretical advances and practical developments for implementing data extraction.
Stepanyan, K. +4 more
core +1 more source
Evaluation of Unsupervised Information Extraction
Unsupervised methods gain more and more attention nowadays in information extraction area, which allows to design more open extraction systems. In the domain of unsupervised information extraction, clustering methods are of particular importance. However, evaluating the results of clustering remains difficult at a large scale, especially in the absence
Wang, W +3 more
openaire +3 more sources

