Results 61 to 70 of about 1,239,647 (288)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Cascaded Feature Selection for Enhancing the Performance of Collaborative Recommender System

open access: yesAdvances in Electrical and Computer Engineering, 2018
Most of collaborative recommender systems (CRSs) rely on statistical and data analysis methods for comparing users. However, dealing with them using machine learning techniques seems to be more appropriate.
AL-SHAMRI, M. Y. H.   +4 more
doaj   +1 more source

Nonlinear Non-Gaussian Estimation Using Maximum Correntropy Square Root Cubature Information Filtering

open access: yesIEEE Access, 2020
This paper concerns the nonlinear filter designing methods in the information space of the nonlinear systems with non-Gaussian noises. Firstly, the prediction information vector is obtained by the traditional square root cubature information filtering ...
Xiaoliang Feng   +4 more
doaj   +1 more source

Document Filtering for Long-tail Entities

open access: yes, 2016
Filtering relevant documents with respect to entities is an essential task in the context of knowledge base construction and maintenance. It entails processing a time-ordered stream of documents that might be relevant to an entity in order to select only
Allan J.   +16 more
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Avoiding congestion in recommender systems

open access: yesNew Journal of Physics, 2014
Recommender systems use the historical activities and personal profiles of users to uncover their preferences and recommend objects. Most of the previous methods are based on objects’ (and/or users’) similarity rather than on their difference.
Xiaolong Ren   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Bayesian Nonlinear Filtering via Information Geometric Optimization

open access: yesEntropy, 2017
In this paper, Bayesian nonlinear filtering is considered from the viewpoint of information geometry and a novel filtering method is proposed based on information geometric optimization.
Yubo Li   +5 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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