Results 261 to 270 of about 5,907,803 (347)

Drivers of summer Arctic sea-ice extent at interannual time scale in CMIP6 large ensembles revealed by information flow. [PDF]

Sci Rep
Docquier D, Massonnet F, Ragone F, Sticker A, Fichefet T, Vannitsem S.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Structure-inclusive similarity based directed GNN: a method that can control information flow to predict drug-target binding affinity. [PDF]

Bioinformatics
Huang J, Sun C, Li M, Tang R, Xie B, Wang S, Wei JM.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Impaired brain-heart axis in focal epilepsy: Alterations in information flow and implications for seizure dynamics. [PDF]

Netw Neurosci
Frassineti L, Catrambone V, Lanatà A, Valenza G.   +3 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Cholinergic heterogeneity facilitates synchronization and information flow in a whole-brain model

Dalla Porta L, Fousek J, Destexhe A, Sanchez-Vives MV.   +3 more
europepmc   +1 more source

Ensemble dynamics and information flow deduction from whole-brain imaging data. [PDF]

PLoS Comput Biol
Toyoshima Y, Sato H, Nagata D, Kanamori M, Jang MS, Kuze K, Oe S, Teramoto T, Iwasaki Y, Yoshida R, Ishihara T, Iino Y.   +11 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Survey of Media Forms and Information Flow Models in Microsystems Companies

, 2010
Christopher Durugbo, Ashutosh Tiwari, Jeffery R. Alcock   +2 more
openalex   +2 more sources