Results 111 to 120 of about 2,380,668 (305)
Two-Stage Document Length Normalization for Information Retrieval [PDF]
ACM Transactions on Information Systems, 2015 The standard approach for term frequency normalization is based only on the document length. However, it does not distinguish the verbosity from the scope, these being the two main factors determining the document length. Because the verbosity and scope have largely different effects on the increase in term frequency, the standard approach can easily ...
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Predicting and Analyzing the Length of Study-Time Case Study: Computer Science Students
ComTech, 2017 The length of study-time is one of the important issues in higher education. The goal of this research was to predict and analyze the length of studytime in the early stage of Computer Science students in X University.
Teny Handhayani, Lely Hiryanto
doaj +1 more source
Randomness and Noise in Information Systems [PDF]
, 2013 This dissertation is devoted to the study of randomness and noise in a number of information systems including computation systems, storage systems, and natural paradigms like molecular systems, where randomness plays important and distinct roles ...
Zhou, Hongchao
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Telomere Length and Distribution in Three Developmental Stages [PDF]
, 2014 Telomeres are specialised nucleoprotein structures present at the ends of each chromatid that function to maintain genome stability. It is well established that a gradual decline in telomere length is associated with the process of cellular ageing, and ...
Digital Scientific, Turner, Kara Jane
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Joint Source-Channel Decoding of Variable-Length Codes with Soft Information: A Survey
EURASIP Journal on Advances in Signal Processing, 2005 Multimedia transmission over time-varying wireless channels presents a number of challenges beyond existing capabilities conceived so far for third-generation networks. Efficient quality-of-service (QoS) provisioning for multimedia on these channels may
Siohan Pierre, Guillemot Christine
doaj +1 more source
Information-Theoretical Criteria for Characterizing the Earliness of Time-Series Data
Entropy, 2019 Biomedical signals constitute time-series that sustain machine learning techniques to achieve classification. These signals are complex with measurements of several features over, eventually, an extended period.
Mariano Lemus +4 more
doaj +1 more source