Results 171 to 180 of about 22,798,456 (294)

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

To Bridge the Hepatitis B Diagnosis Gap in Africa, Innovation Must Go Beyond Digital. [PDF]

J Med Internet Res
Muzaki S.
europepmc   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Development and Internal Validation of the CLIMPOUT Score: A Multimodal Prediction Model for Neurological Outcome After Pediatric Intracerebral Hemorrhage. [PDF]

Diagnostics (Basel)
Pazos E, Bobillo-Perez S, Farras-Riu M, Cambra-Lasaosa FJ, Hernandez-Platero L, Muchart J, Romagosa-Pérez J, Stephan-Otto C, Jordan I, Balaguer M.   +9 more
europepmc   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

The Soil-Plant Coupling Principle (SPCP): A Conceptual Framework for Diagnosing Hidden Ecosystem Vulnerability. [PDF]

Plants (Basel)
Sofo A, Crecchio C, Addesso R, Yaghoubi Khanghahi M.   +3 more
europepmc   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

National Essential Diagnostics List development as an opportunity to expand frontline diagnostic testing at barangay health stations in the Philippines. [PDF]

Trop Med Health
Kanamori S, Evangelista NM, Egami Y, Marayag NG, Cruz-Yañez S, Dela Resma Villanueva AF, Uechi M, Kiyohara H, Dolor MKYD, Ramones RAJ, Duazo AA, Fujita M.   +11 more
europepmc   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Multimodal Imaging of a Post-Traumatic Cervical Arteriovenous Fistula with Concomitant Pseudoaneurysm After a Gunshot Wound Treated with a Covered Stent-Graft. [PDF]

Diagnostics (Basel)
Chlabicz M, Stypułkowski Ł, Jadeszko M, Chlabicz M, Głowiński J.   +4 more
europepmc   +1 more source