Results 91 to 100 of about 21,141,109 (305)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Information Research: An International Electronic Journal, 1996 A study of the management information needs of academic Heads of Department in universities, using a Critical Success Factors approach, was conducted in 1994/1995. A sample of sixteen English universities was developed, based principally on age, history,
Brendan Loughridge
doaj
Huli yanjiu, 2023 ObjectiveTo develop a fertility information needs assessment questionnaire for breast cancer patients of childbearing age，and to test its reliability and validity.MethodsThrough literature analysis，12 cases of breast cancer patients were interviewed by ...
WANG Qi +3 more
doaj
Contextual queries and situated information needs for mobile users [PDF]
, 2010 The users of mobile devices increasingly use networked services to address their information needs. Questions asked by mobile users are strongly influenced by contextual factors such as location, conversation and activity.
Chang, Carole +2 more
core +1 more source
Understanding Information Needs
, 2018 Understanding what the user is looking for is at the heart of delivering a quality search experience. The focus of this chapter is on obtaining semantically enriched representations of search queries with the help of knowledge repositories. Specifically,
K. Balog
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
CONSUMER CLUSTERS AND FOOD SAFETY INFORMATION NEEDS [PDF]
The work presented here was conducted as part of an EU-funded five year project investigating pathogens in the food chain, called "Control and prevention of emerging and future pathogens at cellular and molecular level throughout the food chain". Using a
Hall, Clare
core +1 more source
Collaboration and Connection: How Foundations Partner Effectively to Address Their Community's Information Needs [PDF]
, 2012 Offers examples and tips for partnering with the public, private, and nonprofit sectors on community news and information projects, including finding the right partner by assessing organizational capacity, community assets, compatibility, and ...
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source