Results 91 to 100 of about 8,126,970 (354)

CONSUMER CLUSTERS AND FOOD SAFETY INFORMATION NEEDS [PDF]

open access: yes
The work presented here was conducted as part of an EU-funded five year project investigating pathogens in the food chain, called "Control and prevention of emerging and future pathogens at cellular and molecular level throughout the food chain". Using a
Hall, Clare
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Needs Assessment in Postgraduate Medical Education:A Review [PDF]

open access: yes, 2002
Although the concept of needs assessment in continuing medical education is well accepted, there is limited information on needs assessment in postgraduate medical education.
Hilliard MD, EdD, Robert   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Reading interest and information needs of persons with visual impairment in Nigeria

open access: yesSouth African Journal of Libraries and Information Science, 2010
Information materials can only become usable to persons with visual impairment when they are transcribed into alternative formats. Over time, the transcription and provision of alternative formats in Nigeria by libraries has not been based on users ...
’Niran Adetoro
doaj   +1 more source

What is the Impact of Blended Learning Including Micro-Learning on Manager Learning and Behavior Change vs. Impact of Classroom Learning? [PDF]

open access: yes, 2016
Today’s learning trends show that with more information and technology available, a globalized workforce, and a changing way we learn, corporate learning particularly manager training needs to meet the following criteria: Knowledge should be on demand
Avery, Alex
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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