Options for meeting longitudinal information needs: a preliminary investigation [PDF]
The aim of this paper is to identify the main future requirements for longitudinal data for research and policy purposes, and to discuss how well existing data sources could meet these requirements, as well as options for addressing the gaps.
core
An International Prospectus for Library & Information Professionals: Development, Leadership and Resources for Evolving Patron Needs [PDF]
, 2007 The roles of library and information professionals must change and evolve to: 1. accommodate needs of tech-savvy patrons; 2. thrive in the Commons & Library 2.0; 3. provide integrated, just-in-time services; 4. constantly update and enhance technology; 5.
Bailey, D. Russell
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Product Oriented Modelling Concept: Holons for systems synchronisation and interoperability [PDF]
, 2006 Nowadays, enterprises are confronted to growing needs for traceability, product genealogy and product life cycle management. To meet those needs, the enterprise and applications in the enterprise environment have to manage flows of information that ...
Baïna, Salah +2 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Developing Integrated Waste Management Systems: Information Needs and the Role of Locally Based Data [PDF]
, 2003 No abstract ...
Burnley, Stephen +3 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
پیاورد سلامت, 2014 Background and Aim: In order to better design an electronic health record system in the country, determining standardized data elements for creating an integrated information system is important. In this study, the minimum data set of radiology reporting
Maryam Ahmadi, Azadeh Bashiri
doaj
New Forms of Scientific Communication for Research Intensification [PDF]
Eastern European Journal of Regional Studies, 2016 Development of an effective system of interaction between the scientist and scientific library will optimize the information services for scientists and will promote the development of national science on the basis of new forms of scientific ...
Oxana SAVCIUC, Elena RAILEAN
doaj
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source