Results 131 to 140 of about 21,141,109 (305)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
#Socialtagging: Defining its Role in the Academic Library [PDF]
, 2011 The information environment is rapidly changing, affecting the ways in which information is organized and accessed. User needs and expectations have also changed due to the overwhelming influence of Web 2.0 tools.
Ammer, Annalise, Bertel, Katherine
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Forming an electronic library in a research institution as an integration process
Библиосфера, 2012 The author describes the formation of an electronic library in a research institute as a multi-aspect integration process.
O. I. Levchenko
doaj
Reduce Response Time: Get Hooked on a Wiki [PDF]
, 2007 Managing the flow of information both within the IT department and to our customers is one of our greatest challenges in the Office of Technology Information at Valparaiso University. To be successful, IT staff first need to acquire the right information
Klein, Rebecca +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 13: The information-seeking habits and practices of engineers [PDF]
It is argued that only by maximizing the research and development process can the United States maintain and possibly capture its international competitive edge.
Pinelli, Thomas E.
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source