Results 141 to 150 of about 8,126,970 (354)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Evaluation of VICAR software capability for land information support system needs [PDF]

open access: yes
A preliminary evaluation of the processing capability of the VICAR software for land information support system needs is presented. The geometric and radiometric properties of four sets of LANDSAT data taken over the Elk River, Idaho quadrangle were ...
Yao, S. S.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Developing Community‐Informed Communication Resources to Improve Human Papillomavirus Vaccine Uptake in Tonga

open access: yesHealth Expectations
Introduction Despite high coverage of routine childhood vaccines, uptake of the human papillomavirus (HPV) vaccine in the Pacific Island nation of Tonga has been slow.
Yasmin Mohamed   +20 more
doaj   +1 more source

The Information Behavior of Indonesian Faculty Members on Social Media

open access: yesJournal of Information Science Theory and Practice, 2019
Currently there are many groups of Indonesian faculty members on social media. This research aims to find out the information behavior of Indonesian faculty members on social media, especially on Facebook, Telegram, and WhatsApp.
Kurniasih, Nuning
doaj   +1 more source

Choosing the appropriate treatment setting: which information and decision-making needs do adult inpatients with mental disorders have? A qualitative interview study

open access: gold, 2018
Laura Kivelitz   +7 more
openalex   +2 more sources

Applying remote sensing and GIS techniques in solving rural county information needs [PDF]

open access: yes
The project designed was to acquaint county government officials and their clientele with remote sensing and GIS products that contain information about land conditions and land use.
Fernandez, R. Norberto   +2 more
core   +1 more source

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