Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Patient Education and Levels of Disease-Specific Information Needs Among Individuals With Oral Epithelial Dysplasia. [PDF]
Alamoudi W +4 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Information Deficits, Information Needs, and Preferences Regarding eHealth in a Dutch Population With Metabolic Dysfunction-Associated Steatotic Liver Disease: Cross-Sectional Survey Study. [PDF]
Oude Veldhuis S +4 more
europepmc +1 more source
Exchange Rate and Related Economic Exposures: A Theory for Management Strategy and Information Needs
Lars Oxelheim, Clas Wihlborg
openalex +1 more source
Digital ID Management Which Needs to Strengthen the Function of Protecting Personal Information
Kyoil Chung
openalex +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Assessment of the knowledge landscape, information needs and attitude towards decision support systems among hemp farmers in Florida. [PDF]
Hopf A +4 more
europepmc +1 more source

