Results 271 to 280 of about 8,126,970 (354)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Identifying Priority Science Information Needs for Managing Public Lands. [PDF]

Environ Manage
Carter SK, Haby TS, Samuel EM, Foster AC, Meineke JK, McCall LE, Burton MK, Domschke CT, Espy LD, Gilbert MA.   +9 more
europepmc   +1 more source

Exploring health information needs and preferences of culturally and linguistically diverse (CALD) women during pregnancy: A mixed methods study

C. Harrison, Nitya Nagesh, Bonnie R Brammall, Thara Govindaraju, Rebecca L. Madill, Gretchen Coombs, Daphne Flynn, Myra Thiessen, Helena Teede   +8 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Information Needs of Patients With Head and Neck Cancer and Their Supports in Relation to Treatment Management Choices: Scoping Review.

JMIR Cancer
Stringer E, Rio LH, Leitz L, Prisman E, Borycki E, Kushniruk A, Livergant J, Smith S.   +7 more
europepmc   +1 more source

Analysis of health information needs of elderly patients with chronic diseases based on Kano Model: a descriptive cross-sectional study. [PDF]

BMC Geriatr
Tang Y, Deng X, Chen C, You L, Gong J, Liu X, Zhou J.   +6 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Unmet maternal health information needs and mass media exposure for maternal health among women in the Gedeo zone, South Ethiopia. [PDF]

Front Public Health
Tesfa GA, Getnet A, Seboka BT.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source