Results 281 to 290 of about 8,126,970 (354)

Information Needs of Australian Families Living with Craniosynostosis: A Qualitative Study. [PDF]

Cleft Palate Craniofac J
Osborn AJ, Roberts RM, Dorstyn DS.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Explaining the unmet information needs of family carers of people with dementia: a theoretical model of information behaviour. [PDF]

BMC Geriatr
De Poli C.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Information Needs of State-Level Asthma Programs: Recommendations to Increase Accessibility. [PDF]

Int J Environ Res Public Health
Fox M, Joseph A, Parimi N, Huh H.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Exploring Older Adult Cancer Survivors' Digital Information Needs: Qualitative Pilot Study.

JMIR Cancer
Newton L, Monkman H, Fullerton C.
europepmc   +1 more source

E-cigarette use and health information needs among a university student population in Melbourne, Australia. [PDF]

Front Public Health
Kamoni T, Selamoglu M, Osadnik C, Madawala S, Kotwas S, Turudia K, Barton C.   +6 more
europepmc   +1 more source