Results 41 to 50 of about 637,303 (268)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

«Arktisk blokade»: en russisk informasjonsoperasjon mot Norge

Internasjonal Politikk
Russlands invasjon av Ukraina bryter med et grunnleggende prinsipp i den europeiske sikkerhetsarkitekturen: respekten for territorielle grenser. I denne casestudien ser vi på en hendelse hvor Russland i 2022 utfordret Norges grenser gjennom kampanjer i ...
Karen-Anna Eggen, Siri Strand
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

CYBERSECURITY AS AN ELEMENT OF DEMOCRATIC CONSOLIDATION: LESSONS FROM KHARKIV REGION

Вісник Харківського національного університету імені В. Н. Каразіна: Серія "Питання політології"
In the context of hybrid warfare and targeted information aggression, the issue of cybersecurity is gaining particular importance not only as a technical challenge, but also as a key factor in ensuring national, political and social stability ...
Oleksandra Zinchenko
doaj   +1 more source

Simulation-based evaluation of operating room management policies

BMC Health Services Research, 2021
Background Since operating rooms are a major bottleneck resource and an important revenue driver in hospitals, it is important to use these resources efficiently.
Jan Schoenfelder, Sebastian Kohl, Manuel Glaser, Sebastian McRae, Jens O. Brunner, Thomas Koperna   +5 more
doaj   +1 more source

Mind games setting conditions for successful counterinsurgency military information support operations [PDF]

, 2010
The purpose of this study is to determine what actions can be taken by American military forces to set conditions for conducting effective Military Information Support Operations (MISO) campaigns in counterinsurgency (COIN) conflicts.
Davis, Henry B.
core  

Russian Information Operations

, 2021
Russian Information Operations examines the historical development of Russian information operations from 1989 to 2021, paying particular attention to the role technology, specifically the Internet and social media networks (SMNs), has played in ...
Sarah Morrison (12302849)
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

An investigation of the COVID-19 impact on liver cancer using exploratory and predictive analytics

Healthcare Analytics
This study presents the influence of COVID-19 and the pandemic on individuals diagnosed with hepatocellular carcinoma and intrahepatic cholangiocarcinoma, the two most common types of primary liver cancer.
Victor Chang, Rameshwari Mukeshkumar Patel, Meghana Ashok Ganatra, Qianwen Ariel Xu   +3 more
doaj   +1 more source