Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source
"No more COVID-19 messages via social media, please": the mediating role of COVID-19 message fatigue between information overload, message avoidance, and behavioral intention. [PDF]
Sun J, Lee SK.
europepmc +1 more source
Cancer Information Overload Across Time: Evidence from Two Longitudinal Studies. [PDF]
Lillie H +4 more
europepmc +1 more source
A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy
This article presents a novel magnetic aspiration catheter (MAC) that can be both actively steered and undergo distal‐end expansion via externally applied magnetic fields. The MAC facilitates precise branch selection and enhances clot engagement by improving endovascular navigation and aspiration efficiency. Phantom experiments validate its feasibility
Hakjoon Lee +7 more
wiley +1 more source
The information overload, immunology and their relationship to world health. [PDF]
Bretscher PA.
europepmc +1 more source
Avoiding real news, believing in fake news? Investigating pathways from information overload to misbelief. [PDF]
Tandoc EC, Kim HK.
europepmc +1 more source
High‐Speed Altitude Regulation With Neuromorphic Camera and Lightweight Embedded Computation
Neuromorphic cameras deliver rapid, high‐dynamic‐range sensing but overwhelm embedded processors at high speeds. This work presents a lightweight, optimized Lucas–Kanade optical flow method with parallelization, gyroscopic derotation, and adaptive event slicing.
Simon L. Jeger +3 more
wiley +1 more source
This study proposes a deep learning approach to evaluate the fatigue crack behavior in metals under overload conditions. Using digital image correlation to capture the strain near crack tips, convolutional neural networks classify crack states as normal, overload, or recovery, and accurately predict fatigue parameters.
Seon Du Choi +5 more
wiley +1 more source

