Results 51 to 60 of about 20,164,188 (352)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Budget of the Federal Republic of Germany as a Source for Library and Information Policy
Контуры глобальных трансформаций: политика, экономика, право, 2023 The article examines the budgetary financing of the German library and information policy based on the analysis of expenditure items of the federal budget of the Federal Republic of Germany.
S. V. Sokolov
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
ІНФОРМАЦІЙНА ПРИСУТНІСТЬ УРСР У СВІТІ В ДОБУ ПЕРЕБУДОВИ (1985–1990 рр.) [PDF]
Storìnki Istorìï, 2015 The article highlights the process of changing the information policy of the Ukrainian SSR during the so-called «perestroika» (restructuring) 1985–1990 years and its impact on the nature of the informational presence of Ukraine in the world.
О. В. Махно
doaj
Opportunities for information sharing: case studies [PDF]
, 2015 Personal information provided to government and non-government service providers is highly sensitive. Appropriate collection, management and storage of personal information are critical elements to citizen trust in the public sector.
Ahram Choi +4 more
core
An Analysis of the Value of Information when Exploring Stochastic, Discrete Multi-Armed Bandits
, 2018 In this paper, we propose an information-theoretic exploration strategy for stochastic, discrete multi-armed bandits that achieves optimal regret. Our strategy is based on the value of information criterion.
Principe, Jose C., Sledge, Isaac J.
core +2 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Imperfection Information, Optimal Monetary Policy and Informational Consistency [PDF]
, 2013 This paper examines the implications of imperfect information (II) for optimal monetary policy with a consistent set of informational assumptions for the modeller and the private sector an assumption we term the informational consistency.
Levine, P., Pearlman, J., Yang, B.
core +1 more source
Energy-saving Resource Allocation by Exploiting the Context Information
, 2015 Improving energy efficiency of wireless systems by exploiting the context information has received attention recently as the smart phone market keeps expanding.
Xiong, Zixiang +2 more
core +1 more source
Geo-Spatial Information Science, 2017 The 2030 Agenda for Sustainable Development provides a new global policy to guide the way countries collectively manage and transform the social, economic, and environmental dimensions of people and the planet over the next 15 years.
Greg Scott, A. Rajabifard
semanticscholar +1 more source