E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Editorial: Exploring female intuition: insights into gendered information processing. [PDF]
Front SociolIsenman L, Sinclair M.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Cerebellar tonic inhibition orchestrates the maturation of information processing and motor coordination. [PDF]
Exp Mol MedKwon J +7 more
europepmc +1 more source
Understanding the Information Security Awareness Process in Real Estate Organizations Using the SECI Model [PDF]
, 2014 Deepa Mani +2 more
openalex
A distributed expectation maximization-principal component analysis monitoring scheme for the large-scale industrial process with incomplete information [PDF]
, 2019 Xuanyue Wang +3 more
openalex +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Linguistic structure from a bottleneck on sequential information processing. [PDF]
Nat Hum BehavFutrell R, Hahn M.
europepmc +1 more source
Identification of rainwater harvesting sites using the analytic hierarchy process and geographic information systems in the Khemisset semi-arid region, Morocco [PDF]
Aziz Bourass +5 more
openalex +1 more source