Results 191 to 200 of about 3,451,670 (219)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Ophthalmic health communication in the video-based social media era: A narrative review of information quality, engagement dynamics, and professional education. [PDF]

Digit Health
Yang Y, Ren Y, Liu L, Li Y, Lin X.
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

How accurate are ChatGPT-4 responses in chronic urticaria? A critical analysis with information quality metrics. [PDF]

World Allergy Organ J
Cherrez-Ojeda I, Faytong-Haro M, Alvarez-Muñoz P, Larco JI, de Arruda Chaves E, Rojo I, Moncayo CV, Ramon GD, Rodas-Valero G, Kocatürk E, Mosnaim GS, Robles-Velasco K.   +11 more
europepmc   +1 more source

Dataset on patient education and digital information quality in knee cartilage restoration with matrix-induced autologous chondrocyte implantation (MACI). [PDF]

Data Brief
Vicioso C, Terry HL, Neijna AG, Strickland SM.   +3 more
europepmc   +1 more source

Assessment of information quality and reliability on ankle sprains in short videos from Douyin and Bilibili. [PDF]

Sci Rep
Li Z, Zhong Z, Deng X, Liao F, Hu Y, Liu X.   +5 more
europepmc   +1 more source

Evaluation of the information quality related to osteoporosis on TikTok. [PDF]

BMC Public Health
Li A, Xing Q, Zhang Y, Zhan W, Zhu S, Lou L, Jiang C, Guo Z, Sun H.   +8 more
europepmc   +1 more source

Information quality of videos related to esophageal cancer on tiktok, kwai, and bilibili: a cross-sectional study. [PDF]

BMC Public Health
Zhu W, He B, Wang X, Du Y, Young K, Jiang S.   +5 more
europepmc   +1 more source

An Information Quality Framework for Managed Health Care. [PDF]

J Healthc Leadersh
Crossette-Thambiah G, Berleant D, AbuHalimeh A.   +2 more
europepmc   +1 more source

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Time to add screening for financial hardship as a quality measure?

Ca-A Cancer Journal for Clinicians, 2021
Ya-Chen Tina Shih, Cathy J Bradley, Syed Yousuf Zafar   +2 more
exaly