Results 111 to 120 of about 7,826,212 (327)

Visualisation of the information resources for cell biology [PDF]

open access: yes, 2005
Intelligent multimodal interfaces can facilitate scientists in utilising available information resources. Combining scientific visualisations with interactive and intelligent tools can help create a “habitable” information space.
Malchanau, Andrei   +2 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

COMMERCIALIZATION OF INNOVATIVE ACTIVITIES AND ESSENCE OF INNOVATIVE ENTREPRENEURSHIP

open access: yesAdvanced Engineering Research, 2011
The conceptual framework of commercialization in the market system is revealed. The essence of the innovation business in the regulation of the commercial innovative activities is analyzed.
Boris М. Getman   +2 more
doaj  

HaIRST: Harvesting Institutional Resources in Scotland Testbed. Final Project Report [PDF]

open access: yes, 2005
The HaIRST project conducted research into the design, implementation and deployment of a pilot service for UK-wide access of autonomously created institutional resources in Scotland, the aim being to investigate and advise on some of the technical ...
Dunsire, Gordon
core  

African-American Mental Health Community: Information Needs, Barriers, and Gaps [PDF]

open access: yes, 2020
This paper articulates the importance of African Americans regarding mental health: how they obtain information, lack of available resources, internal and external pressures of receiving help, and the gathering of their information from non-traditional ...
Jackson, Stephanie
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Return on Instruction: Methods for Assessing the Impact of Information Literacy Instruction on the Use of Electronic Resources [PDF]

open access: yes, 2015
Moving from simplistic, open web search strategies sufficient for high school level work to independently navigating the complex system of information sources available on college campuses is a developmental milestone for undergraduate students.
Branch, Nicole A., McKeigue, Elizabeth
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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