Results 131 to 140 of about 19,228,099 (387)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

On-Demand Based Wireless Resources Trading for Green Communications [PDF]

open access: yesarXiv, 2011
The purpose of Green Communications is to reduce the energy consumption of the communication system as much as possible without compromising the quality of service (QoS) for users. An effective approach for Green Wireless Communications is On-Demand strategy, which scales power consumption with the volume and location of user demand.
arxiv  

Information as a corporate resource

open access: yesInformation Services & Use, 1989
Developments in computing and telecommunication have brought about fundamental changes in worldwide business practices. Just as the concept of corporate finance has grown beyond keeping track of income, expenses, and assets, our concept of information as a corporate resource must go beyond discussion of databases, the value and cost information ...
openaire   +2 more sources

Redesigning Information Resources for Digital Natives [PDF]

open access: yes, 2008
The influx of Digital Natives into higher education, combined with the introduction of virtual learning environments as the primary means of interaction between students and universities, will have a transformational effect on learning and on library ...
Ball, David   +2 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

The application of digitization and digital marketing for the recovery of Ukraine's economy

open access: yesВісник Харківського національного університету імені В.Н. Каразіна: Серія Економіка
The article explores the potential application of digital technologies and digital marketing for the post-war recovery of Ukraine's economy. The war in Ukraine has led to significant destruction and economic losses, making it crucial to explore pathways ...
N. Nazarenko, A. Nochovka
doaj   +1 more source

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