Results 71 to 80 of about 19,385,628 (381)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

INFORMATION PROVISION OF DISTANCE LEARNING SYSTEM

Інформаційні технології і засоби навчання, 2010
The article deals with the results of the research concerning the relevant information resources elaborated and introduced into the pedagogical process by the author. The peculiarities of the first in Ukraine dictionary on theory and practice of distance
Viacheslav M. Oleksenko
doaj  

Information for Learning Resources' Webwriters [PDF]

, 2016
An amalgamation of resources that will be useful for LR webwriters who are moving their web documents to ...
Rowena Rouse, Tamsin Rothery
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

New Mexico practitioners' access to and satisfaction with online clinical information resources: an interview study using qualitative data analysis software.

Journal of the Medical Library Association, 2015
QUESTIONS What information resources are available to health care practitioners not affiliated with the University of New Mexico? How satisfied are they with those resources? SETTING The state is rural and medically underserved.
Patricia V. Bradley, Christina M. Getrich, G. Hannigan   +2 more
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

SINGER, the System wide Information NEtwork on Genetic Resources of CGIAR [PDF]

, 2009
The System-Wide Information System for Genetic Resources (SINGER) (http://www.singer.cgiar.org/) is an online catalogue of crop collections that provides inventories of conserved agricultural diversity and offers primary access for identifying and locate
Arnaud, Elizabeth, Sarah, Gautier, Skofic, Milko, Sood, Rajesh, Viparthi, Kiran   +4 more
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Database resources of the National Center for Biotechnology Information: update

Nucleic Acids Research, 2004
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biological data made available through ...
David L. Wheeler, D. Church, Ron Edgar, S. Federhen, W. Helmberg, Thomas L. Madden, J. Pontius, G. Schuler, L. Schriml, Edwin Sequeira, Tugba Onal Suzek, T. Tatusova, L. Wagner   +12 more
semanticscholar   +1 more source

INSPIRAL: investigating portals for information resources and learning. Final project report [PDF]

, 2001
INSPIRAL's aims were to identify and analyse, from the perspective of the UK HE learner, the nontechnical, institutional and end-user issues with regard to linking VLEs and digital libraries, and to make recommendations for JISC strategic planning and ...
Brown, S., Currier, S., Ekmekioglu, F.C., JISC (Joint Information Systems Committee) (Funder)   +3 more
core