Results 71 to 80 of about 19,777,480 (367)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Philosophy of creating information resources
Проблеми теорії та методології бухгалтерського обліку, контролю і аналізуInformation has become the main driver of modern society, affecting all spheres of life, from education and science to business and communication. In the context of the global digital transformation, the amount of data generated on a daily basis requires
N.Ya. Marchyshyn
doaj +1 more source
Бюллетень сибирской медицины, 2005 The history of the oldest medical library in Siberia has been presented. There is data of the stock, information resources and the basic activity directions.
N. V. Molodtsova
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
INFORMATION PROVISION OF DISTANCE LEARNING SYSTEM
Інформаційні технології і засоби навчання, 2010 The article deals with the results of the research concerning the relevant information resources elaborated and introduced into the pedagogical process by the author. The peculiarities of the first in Ukraine dictionary on theory and practice of distance
Viacheslav M. Oleksenko
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Journal of the Medical Library Association, 2015 QUESTIONS What information resources are available to health care practitioners not affiliated with the University of New Mexico? How satisfied are they with those resources? SETTING The state is rural and medically underserved.
Patricia V. Bradley +2 more
semanticscholar +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Effects of corruption risks on access to information resources: the question
Проблеми Законності, 2015 The article examines the impact of actual corruption risks in providing access to information resources. Defined objective and subjective factors contributing to the corruption risks and the ways of their reduction.
О. Б. Червякова
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
COMMERCIALIZATION OF INNOVATIVE ACTIVITIES AND ESSENCE OF INNOVATIVE ENTREPRENEURSHIP
Вестник Донского государственного технического университета, 2018 The conceptual framework of commercialization in the market system is revealed. The essence of the innovation business in the regulation of the commercial innovative activities is analyzed.
Boris М. Getman +2 more
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