Results 71 to 80 of about 19,228,099 (387)

Database resources of the National Center for Biotechnology Information

Nucleic Acids Res., 2014
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for ...
David L. Wheeler, T. Barrett, Dennis A. Benson, Stephen H. Bryant, Kathi Canese, V. Chetvernin, Deanna M. Church, Michael DiCuccio, Ron Edgar, S. Federhen, Lewis Y. Geer, Wolfgang Helmberg, Yuri Kapustin, D. L. Kenton, Oleg Khovayko, D. Lipman, Thomas L. Madden, D. Maglott, J. Ostell, K. Pruitt, Gregory D. Schuler, L. M. Schriml, Edwin Sequeira, Stephen T. Sherry, K. Sirotkin, A. Souvorov, G. Starchenko, Tugba Onal Suzek, R. Tatusov, T. Tatusova, Lukas Wagner, E. Yaschenko   +31 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

COMMERCIALIZATION OF INNOVATIVE ACTIVITIES AND ESSENCE OF INNOVATIVE ENTREPRENEURSHIP

Вестник Донского государственного технического университета, 2018
The conceptual framework of commercialization in the market system is revealed. The essence of the innovation business in the regulation of the commercial innovative activities is analyzed.
Boris М. Getman, Olga А. Nenakhova, Victoria А. Chistova   +2 more
doaj  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

FINANCIAL STATEMENTS OF MULTILEVEL SYSTEM OF CONSUMER COOPERATION IN UKRAINE, ITS INFORMATIONAL COMPLIANCE WITH MODERN EUROPEAN REQUIREMENTS

USV Annals of Economics and Public Administration, 2016
More than 120 countries use the International Financial Reporting Standards (IFRS) and the International Accounting Standards (IAS). The Association Agreement between Ukraine and the EU obliges Ukraine to European convergence of accounting.
Stepan KOSHKAROV
doaj  

Information Transfer Among Grape Producers in the Western United States on Pest and Disease Management

PhytoFrontiers
Knowledge about how producers subjectively assess and communicate about different information resources can help optimize Agricultural Extension efforts.
Sarah R. Lowder, Michelle M. Moyer, Monica L. Cooper, Jay W. Pscheidt, Walter F. Mahaffee   +4 more
doaj   +1 more source

Resource Logics with a Diminishing Resource [PDF]

arXiv, 2018
Model-checking resource logics with production and consumption of resources is a computationally hard and often undecidable problem. We introduce a simple and realistic assumption that there is at least one diminishing resource, that is, a resource that cannot be produced and every action has a non-zero cost on this resource.
arxiv  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

A Model for Evaluating Damage Inflicted Dye Destructive Events in the Computer Information System

Безопасность информационных технологий, 2010
Here we present a model to evaluate the mean expectation of damage inflicted by destructive events in the computer information system. A condition of damage reduction is deduced. Some ways how to guarantee supply of this condition are presented.
S. V. Zapechnikov
doaj