Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Picture Preview Generation for Interactive Educational Resources
Complexity, 2021 With the development of network technology, many online educational resource platforms have emerged, and the number of resources on these platforms is increasing dramatically. Compared with the traditional resources, the interactive educational resources
Jianxiong Wang +3 more
doaj +1 more source
Computerized Management Information Systems Resources and their Relationship to the Development of Performance in the Electricity Distribution Company in Gaza [PDF]
, 2016 This paper aims to identify computerized management information systems resources and their relationship to the development of performance in the Electricity Distribution Company in Gaza. This research used two dimensions.
Abu Naser, Samy S., Al Shobaki, Mazen J.
core
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Autonomic grid architecture based on information pool protocol
Tongxin xuebao, 2008 An information pool based grid architecture （IPBGA） was presented. Requests from resources for tasks and appeals from tasks for resources were upgraded as information services by using information pool protocol （IPP）.
CHEN Zhi-gang +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns +4 more
wiley +1 more source
Challenges in multidisciplinary cancer care among general surgeons in Canada
BMC Medical Informatics and Decision Making, 2008 Background While many factors can influence the way that cancer care is delivered, including the way that evidence is packaged and disseminated, little research has evaluated how health care professionals who manage cancer patients seek and use this ...
McLeod Robin S +4 more
doaj +1 more source
Exploring general practitioners’ perception of the value of natural history information and their awareness and use of guidelines’ resources to support antibiotic prescribing for self-limiting infections: a qualitative study in Australian general practice [PDF]
, 2023 Kwame Peprah Boaitey +3 more
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Considerations on the selection and prioritization of information security solutions
Audit Financiar, 2016 This paper provides a set of guidelines that can be used for prescribing a methodology or a detailed process for selecting and prioritizing security projects or solutions.
Maria Cristina RĂDULESCU
doaj +1 more source