Results 91 to 100 of about 2,579,110 (275)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

СОВРЕМЕННОЕ СОСТОЯНИЕ И ТЕНДЕНЦИИ РАЗВИТИЯ ИНФОРМАЦИОННЫХ РЕСУРСОВ И ТЕХНОЛОГИЙ

open access: yesБиблиосфера, 2010
The data regarding the development of information technologies, the growth of information resources, the formation of information society in Russia. We consider the main trends of development of the Internet, using services provided by a global network ...

doaj  

The Deadly Details: How Clear and Complete Are Publicly Available Sources of Human Rabies Information?

open access: yesTropical Medicine and Infectious Disease
Human rabies is preventable but almost always fatal once symptoms appear, causing 59,000 global deaths each year. Limited awareness and inconsistent access to post-exposure prophylaxis hinder prevention efforts.
Natalie Patane   +5 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Informing the general public about cell migration - a public engagement resource

open access: yes, 2013
Outreach activities become an increasingly important part of a researcher's life, out of social responsibility as well as to meet expectations by research funding institutions. Yet, outreach activities are little supported by resources which provide guidance, strategies, examples and materials, and researchers are widely left alone with the task of re ...
Sumner, Jessica, Prokop, Andreas
openaire   +2 more sources

Complex information resources of a research library: modernization and development

open access: yesБиблиосфера, 2018
Library scientists have been actively considering the ways to improve various aspects of library activities recent decades. The most studied problems are the following: libraries innovative development in general, information systems updating, e ...
I. G. Yudina, E. A. Bazyleva
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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