Results 101 to 110 of about 5,261,148 (345)
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr+5 more
wiley +1 more source
Complex information resources of a research library: modernization and development
Library scientists have been actively considering the ways to improve various aspects of library activities recent decades. The most studied problems are the following: libraries innovative development in general, information systems updating, e ...
I. G. Yudina, E. A. Bazyleva
doaj +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source
Assessment of self‐reporting reading of medicine's labels and the resources of information about medicines in general public in Malaysia [PDF]
Omar Thanoon Dawood+3 more
openalex +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel+8 more
wiley +1 more source
The Impact of Human Capital on Information Literate Behavior Among Librarians:A case study at University of Diponegoro [PDF]
Information literacy has become one of the key competency needed by any individual in the information age. Librarians as information professionals are required to play its part in developing this competency.
Setyowati, Lis, Yuventia, Yuniwati
core
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti+8 more
wiley +1 more source
There has recently been a major advance with respect to how information fusion is performed. Information fusion has gone from being conceived as a purely hierarchical procedure, as is the case of traditional military applications, to now being regarded collaboratively, as holonic fusion, which is better suited for civil applications and edge ...
Paggi, Horacio+2 more
openaire +5 more sources