Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
European Regions Financing Public e-Services: the Case of EU Structural Funds. [PDF]
EU Structural Funds represent by far the main source of funding for innovation in general and for eservices in particular in the lagging regions of Europe classified into the “Convergence” objective.
Luigi Reggi, Sergio Scicchitano
core
The Influence of Socioeconomic Factors on the Development of Early Number Concepts [PDF]
, 2014 Why are some children entering school unable to count, while others are able to do simple addition? It may be that early experiences, like practice with numbers and extra resources to promote logical thinking, lay the foundation for how children and ...
Caldwell, Brittany Meghan
core +1 more source
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova +5 more
wiley +1 more source
Studying Academic Lawyers' Information-Seeking to Inform the Design of Digital Law Libraries [PDF]
, 2006 We report findings from the initial phase of our study on legal information seeking, which comprised a series of semi-structured interviews and naturalistic observations of academic law students and staff looking for electronic legal information.
Makri, S.
core +1 more source
Long‐Term Temporal Profile of Motor Recovery After Intracerebral Hemorrhage
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Limited data is available to describe the temporal profile of long‐term recovery over 1 year after the stroke in patients with spontaneous intracerebral hemorrhage (ICH). Methods A registered multicentral cohort was conducted to consecutively include non‐herniated supratentorial ICH patients from November 2013 to January 2023 ...
Yan Zheng +24 more
wiley +1 more source
Population, Resources and Development in the Eastern Islands of Fiji: Information for Decision-making. General Report No. 1 of the Unesco/Unfpa Population and Environment Project in the Eastern Islands of Fiji. Man and the Biosphere (MAB) Programme, Project 7: Ecology and Rational Use of Island Ecosystems. Development Studies Centre, Australian National University for Unesco, 1977, 407 pp. [PDF]
, 1978 R. F. Watters
openalex +1 more source
Modelling the Product Development performance of Colombian Companies [PDF]
, 2009 Organised by: Cranfield UniversityThis paper presents the general model of the Product Development Process (PDP) in the Metal mechanics Industry in Barranquilla-Colombia, since this sector contributes significantly to the productivity of this ...
Al-Ashaab, Ahmed +4 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons +8 more
wiley +1 more source