Results 61 to 70 of about 5,261,148 (345)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Developing information services for special library users by designing a low cost digital library : the experiment of NOC-Digital Library [PDF]

, 2010
This research originates from a belief that special libraries in developing countries need to modernise and implement their ICT infrastructure and articulate information policies that will facilitate the exploitation of information resources to the ...
Elaiess, Ramadan
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

ECONOMIC AND INFORMATIONAL SYSTEM OF MONITORING THE PRODUCTION RESOURCES OF THE NEW GENERATION

Vestnik MGSU, 2016
Monitoring of production resources is a large-scale and complicated measure, the results of which are necessary for the state and for private entrepreneurs. There are many approaches to conducting such a monitoring, which firstly base on the information request from the suppliers of the resources by governmental bodies. The authors offer a new approach
openaire   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Income Tax “Need to Knows” for Military Families

EDIS
This publication discusses general information about income tax terminology, general information about income tax rules, rates, and refunds, military-specific income tax challenges, military-specific income tax regulations, five income tax planning tips
Barbara O'Neill, Martie Gillen, Kristen Jowers   +2 more
doaj   +3 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Data Management Training for Graduate Students at a Large Research University

Journal of eScience Librarianship, 2012
This article describes UMass Amherst Libraries data management workshops and online resources developed for graduate students. Although students respond favorably to general “Data Management Basics” workshops, they offer suggestions for improvement and ...
Jessica Adamick, Rebecca C. Reznik-Zellen, Matt Sheridan   +2 more
doaj   +1 more source

Audio-visual Resources and Education

Cuadernos de Documentación Multimedia, 2014
The exponential information growth requires public policies to ensure the universal access to educational resources in general and in particular to quality audiovisual resources.
Beatriz Susana Sevilla
doaj   +1 more source

Measuring quality, reputation and trust in online communities

, 2012
In the Internet era the information overload and the challenge to detect quality content has raised the issue of how to rank both resources and users in online communities.
Cimini, Giulio, Liao, Hao, Medo, Matus
core   +1 more source