Results 61 to 70 of about 5,553,411 (298)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Audio-visual Resources and Education

open access: yesCuadernos de Documentación Multimedia, 2014
The exponential information growth requires public policies to ensure the universal access to educational resources in general and in particular to quality audiovisual resources.
Beatriz Susana Sevilla
doaj   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Designing a site-directory of web resources for a teacher of informatics

open access: yesUkrainian Journal of Educational Studies and Information Technology, 2019
The article is devoted to the study of the process of creating and designing a site-catalogue of modern web resources for its usage by informatics teacher in his professional activities.
Viktoriia Alekseienko, Olena Usata
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Connecting Human and Information Resources in the Generation of Competitive Advantage

open access: yesJournal of the Knowledge Economy
Abstract A key trend in recent decades is a growing standardisation of tangible digital resources. This trend coexists with development in the most advanced organisations of high-level technological, human and organisational resources teams built around advanced digital solutions.
Sergio Camisón-Haba   +2 more
openaire   +4 more sources

Search and Discovery Tools for Astronomical On-line Resources and Services [PDF]

open access: yes, 2000
A growing number of astronomical resources and data or information services are made available through the Internet. However valuable information is frequently hidden in a deluge of non-pertinent or non up-to-date documents.
Egret, Daniel   +2 more
core   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Data Management Training for Graduate Students at a Large Research University

open access: yesJournal of eScience Librarianship, 2012
This article describes UMass Amherst Libraries data management workshops and online resources developed for graduate students. Although students respond favorably to general “Data Management Basics” workshops, they offer suggestions for improvement and ...
Jessica Adamick   +2 more
doaj   +1 more source

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