Results 71 to 80 of about 291,249 (309)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Estudos de avaliação quantitativa e qualitativa de linguagens documentárias: uma síntese bibliográfica

open access: yesPerspectivas em Ciência da Informação
Este estudo apresenta uma síntese bibliográfica sobre as metodologias de avaliação que foram propostas por pesquisadores internacionais e nacionais e utilizadas por indexadores de instituições de ensino e/ou pesquisas atuantes em unidades de informação e/
Vera Regina Casari Boccato   +1 more
doaj   +1 more source

從國際百科的應用展望我國書目資訊系統的發展 From the Utilization of UDAS to Outlook the Development of Bibliographic Information Retrieval System in the R.O.C. [PDF]

open access: yesJiàoyù zīliào yǔ túshūguǎn xué, 1980
無UDAS (Universal Database Access Service) is an international on- line real time information retrieval system. It inaugurated services to the public on Dec. 28. 1979.
Hong-chu Huang
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Challenges in cross-cultural/multilingual music information seeking

open access: yes, 2005
Understanding and meeting the needs of a broad range of music users across different cultures and languages are central in designing a global music digital library.
Lee, Jin Ha   +5 more
core   +1 more source

Integrating methods from IR and QA for geographic information retrieval [PDF]

open access: yes, 2009
This paper describes the participation of GIRSA at Geo- CLEF 2008, the geographic information retrieval task at CLEF. GIRSA combines information retrieval (IR) on geographically annotated data and question answering (QA) employing query decomposition ...
Hartrumpf, Sven   +3 more
core   +1 more source

Evaluation Criteria of Information Retrieval Systems: What We Know and What We Do Not Know

open access: yesIranian Journal of Information Processing & Management, 2014
Evaluation of information retrieval systems is one of the greatest challenges for information science specialists, because determining the performance of a system depends on judgment of the relevance of documents provided by the system to the user's ...
Nadjla Hariri   +3 more
doaj  

PENGEMBANGAN SISTEM TEMU KEMBALI INFORMASI DIGITAL FULLTEXT ARTIKEL JURNAL DI PDII – LIPI

open access: yesBaca: Jurnal Dokumentasi dan Informasi, 2016
One of the tasks in Center for Scientific Documentation and Information – Indonesian Institutes of Sciences (PDII - LIPI) is to disseminate the results of existing research in Indonesia.
Sjaeful Afandi   +2 more
doaj   +1 more source

Multilingual Dictionary of Keywords as a Tool for the Digital Bibliographic Database of World Slavic Linguistics

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2020
The paper presents the structure of a multilingual dictionary of keywords, which is an integral part of the bibliographic database of Slavic linguistics iSybislaw representing the digital information retrieval system (www.isybislaw.ispan.waw.pl).
Paweł Kowalski
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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