Results 51 to 60 of about 733,452 (294)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Locating Source Code Bugs in Software Information Systems Using Information Retrieval Techniques

Big Data and Cognitive Computing, 2022
Bug localization is the process through which the buggy source code files are located regarding a certain bug report. Bug localization is an overwhelming and time-consuming process.
Ali Alawneh, Iyad M. Alazzam, Khadijah Shatnawi   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Information retrieval support systems [PDF]

2002 IEEE World Congress on Computational Intelligence. 2002 IEEE International Conference on Fuzzy Systems. FUZZ-IEEE'02. Proceedings (Cat. No.02CH37291), 2003
Information retrieval support systems (IRSS) are designed with the objective to provide the necessary utilities, tools, and languages that support a user to perform various tasks in finding useful information and knowledge. While existing information retrieval systems (IRS) focus on the search and browsing functionalities, an IRSS focuses on the ...
openaire   +2 more sources

Kidney Segmentation of Histopathological Images with Edge-Aware U-Net to Support Medical Diagnosis and Treatment Planning

Bioengineering
Accurate segmentation of renal anatomical structures is essential for informed clinical decision-making in nephropathology, supporting precise diagnosis, treatment planning, and longitudinal monitoring of kidney diseases. In this work, we propose an Edge-
Esraa Hassan, Amira Samy Talaat, Shaimaa M. Hassan, Sameer Alqassimi, M. A. Elsabagh   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Review on Information Accessing Systems Based on Fuzzy Linguistic Modelling [PDF]

International Journal of Computational Intelligence Systems, 2010
This paper presents a survey of some fuzzy linguistic information access systems. The review shows information retrieval systems, filtering systems, recommender systems, and web quality evaluation tools, which are based on tools of fuzzy linguistic ...
E. Herrera-Viedma, A.G. Lopez-Herrera
doaj   +1 more source

A new metric for patent retrieval evaluation [PDF]

, 2010
Patent retrieval is generally considered to be a recall-oriented information retrieval task that is growing in importance. Despite this fact, precision based scores such as mean average precision (MAP) remain the primary evaluation measures for patent ...
Jones, Gareth J.F., Magdy, Walid
core  

Closing the loop: assisting archival appraisal and information retrieval in one sweep [PDF]

, 2013
In this article, we examine the similarities between the concept of appraisal, a process that takes place within the archives, and the concept of relevance judgement, a process fundamental to the evaluation of information retrieval systems.
Kim, Y., Ross, S.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source