Results 81 to 90 of about 1,097,074 (300)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Hypnopaedia-Aware Machine Unlearning via Psychometrics of Artificial Mental Imagery

open access: yesIEEE Access
Neural backdoors represent insidious cybersecurity loopholes that render learning machinery vulnerable to unauthorised manipulations, potentially enabling the weaponisation of artificial intelligence with catastrophic consequences.
Ching-Chun Chang   +5 more
doaj   +1 more source

Uses and Gratification Theory in Connection with Knowledge and Information Science: A Proposed Conceptual Model

open access: yes, 2016
This paper was aimed at clarifying the links between Uses and Gratification Theory (UGT) and Knowledge and Information Science in both traditional and modern contexts.
Mehrad, Jafar; Professor, Department of Knowledge & Information Science, College of Education & Psychology, Shiraz University, Shiraz, Iran   +1 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Research on the Structures and Features of Netizens' Demand for Popular Science: A Search Data Perspective

open access: yesCultures of Science, 2019
Netizens' demand for popular science could be seen as one important social representation of the public demand for science popularization in the information age.
Liming Wang, Qi Zhong
doaj   +1 more source

The Information Society: advantages and disadvantages [PDF]

open access: yes, 2007
Today, information society has transformed various facets of our life such as the fields of business, education and communication just to mention but a few. The impacts of information society are profound.
Polyviou, Zachos A.
core  

Information Systems Project Post-Mortems: Insights from an Attribution Perspective

open access: yes, 2007
10.1002/asi.20693Journal of the American Society for Information Science and Technology58142255 ...
PAN, Shan Ling   +11 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

CERN to host conference on the Role of Science in the Information Society

open access: yes, 2003
"On December 8-9, CERN will host the Role of Science in the Information Society (RSIS) conference, together with UNESCO, the International Council for Science, and the Third World Academy of Sciences. A Summit Event to the first phase of the World Summit

core  

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