FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Exploring Current Practices, Needs, and Barriers for Expanding Distributed Medical Education and Scholarship in Psychiatry: Protocol for an Environmental Scan Using a Formal Information Search Approach and Explanatory Design. [PDF]
JMIR Res Protoc, 2023 Hazelton L +18 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Analysis of the Conflict between Car Commuter's Route Choice Habitual Behavior and Traffic Information Search Behavior. [PDF]
Sensors (Basel), 2022 Liu K.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Exploring the roles of information search and information evaluation literacy and pre-service teachers' ICT self-efficacy in teaching. [PDF]
Int J Educ Technol High Educ, 2022 Peciuliauskiene P +2 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Evaluation of Instagram’s popularity: Brand cue and message appeal as explanatory variables
Asian Management and Business ReviewThe internet’s ascent has transformed digital marketing, with social media platforms like Instagram becoming essential tools. The “Instagrammable” trend has gained traction in the food industry, using visual appeal to drive business success and expand ...
Putri Anggraini, Muji Gunarto
doaj
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Searching for Internet Web-Information
Journal of Information Processing and Management, 2001 爆発的に増加するインターネットから，目覚ましい進化を遂げつつある検索エンジンを使ったとしても意図する高品質な学術情報源を効率的に入手するのはなかなか容易ではない。図書館が提示したアクセス改善策を2つ挙げる。1つがメタデータで目録を記述した専門分野別検索エンジンのサブジェクト・ゲートウェイである。そして，もう1つが利用者教育・支援を目的とし，図書館員や専門家が電子メールなどを用いて回答を行うデジタル・レファレンスである。効果的なウェブ探索のために，図書館がすべきことは，インターネット，紙媒体の資料，電子資料の3者を統合した情報の道筋（Pathfinder）を発見し，整備することである。
openaire +2 more sources