Results 41 to 50 of about 417,871 (268)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
THE GENERATING RANDOM SEQUENCES WITH THE INCREASED CRYPTOGRAPHIC STRENGTH
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2020 Random sequences are used in various applications in construction of cryptographic systems or formations of noise-type signals. For these tasks there is used the program generator of random sequences which is the determined device. Such a generator, as a
Volodymyr Korchynskyi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
CybersecurityMicroservice architecture faces security issues due to the large scale of services, resulting in a large attack surface. Integrating the concept of “continuous authentication, never trust” from the zero-trust security model into the access control of ...
Zhangwen Li +4 more
doaj +1 more source
A comprehensive review of cyber-physical security risks in new power system
Security and SafetyThis review systematically examines the multifaceted cyber-physical security risks facing new power systems during the global energy transition, with a focus on three critical dimensions.
Huang Huihui +4 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Scientific ReportsX-ray image-based prohibited item detection plays a crucial role in modern public security systems. Despite significant advancements in deep learning, challenges such as feature extraction, object occlusion, and model complexity remain.
Kai Zhao +3 more
doaj +1 more source
Research on the recognition technology of regional network topology boundary
Dianzi Jishu YingyongNetwork boundary recognition is an important step in network topology measurement. Currently, regional network boundary recognition technology is mainly based on sampling detection of regional networks and boundary screening using IP address based ...
Zhang Haoyu +4 more
doaj +1 more source
Influence Maximization with Priority in Online Social Networks
Algorithms, 2020 The Influence Maximization (IM) problem, which finds a set of k nodes (called seedset) in a social network to initiate the influence spread so that the number of influenced nodes after propagation process is maximized, is an important problem in ...
Canh V. Pham +4 more
doaj +1 more source