Results 201 to 210 of about 2,067,027 (330)

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

Advanced Science, EarlyView.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari, Divyaleka Sampath, Paige Eversole, Melissa Ong Yu Lin, Dmitriy A. Bosykh, Gandhi T.K. Boopathy, Aravind Sivakumar, Cheng‐Chun Wang, Ramesh Kumar, Joe Yeong Poh Sheng, Ellen Karasik, Barbara A. Foster, Han Yu, Xiang Ling, Wenjie Wu, Fengzhi Li, Zoë Weaver Ohler, Christine F. Brainson, David W. Goodrich, Wanjin Hong, Sayan Chakraborty   +20 more
wiley   +1 more source

Leveraging blockchain and IoMT for secure and interoperable electronic health records. [PDF]

Sci Rep
Othman SB, Getahun M.
europepmc   +1 more source

Research Trends in Economic Effects of Information Security Certification: Focused on the ISMS (Information Security Management System)

, 2016
Hee-Kyung Kong, Hyo-Jung Jun, Song-Ha Lee, Minseong Kang, Tae-Sung Kim   +4 more
openalex   +2 more sources

Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas

Advanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian, Shuqin Liu, Hongtao Shi, Jianjun Li, Xinglong Wan, Yujiang Sun, Huayun Li, Ning Cao, Zhixi Feng, Teng Zhang, Junjie Wang, Wei Shen   +11 more
wiley   +1 more source

Advanced technique for firmware security analysis through heterogeneous data fusion and knowledge mapping. [PDF]

PLoS One
Xiao P, Xie L, Hang F, Li H.
europepmc   +1 more source

The Semi‐Natural Climate Chambers across Latitudes: A Broadly Applicable Husbandry and Experimental System for Terrestrial Ectotherms under Climate Change

Advanced Science, EarlyView.
Assessing species' vulnerabilities across geographical gradients is essential for biodiversity conservation under climate change. To address this challenge, the semi‐natural climate chamber across latitudes (SCCAL) is developed, a validated system capable of simulating thermal environments for ecological experiments without reliance on water or ...
Bao‐Jun Sun, Hong‐Liang Lu, Kun‐Ming Cheng, Wan‐Li Liu, Xing‐Zhi Han, Luo‐Xin Cui, Xing‐Han Li, Shu‐Ran Li, Xin Hao, Fan Li, Dan‐Yang Wu, Teng Li, Yong‐Pu Zhang, Ji‐Chao Wang, Peng Liu, Wei‐Guo Du   +15 more
wiley   +1 more source

A scoping review of human genetic resources management policies and databases in high- and middle-low-income countries. [PDF]

BMC Med Ethics
Liu H, Liu Y, Zhao Y, Ma Y, Chen Q, Xu H, Wang X, Guo X, Wang H, Chen Z, Zhang S, Han B.   +11 more
europepmc   +1 more source

Determining Information Security Threats for an IoT-Based Energy Internet by Adopting Software Engineering and Risk Management Approaches [PDF]

, 2019
Yu-Tso Chen, C. Derrick Huang
openalex   +1 more source

Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation

Advanced Science, EarlyView.
Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang, Yitao Cheng, Penghui Zhao, Jiageng Cai, Zhaowei Yin, Shaomin Chen, Ge Guo, Chi Zhu, Ke Liu, Lingyun Zu   +9 more
wiley   +1 more source

A secure and scalable IoT access control framework with dynamic attribute updates and policy hiding. [PDF]

Sci Rep
Xu Z, Zhou W, Han H, Dong X, Zhang S, Hu Z.   +5 more
europepmc   +1 more source