Results 171 to 180 of about 577,665 (343)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Menstrual Health of Adolescent Girls in Surat City– A Cross Sectional Study
National Journal of Community Medicine, 2015 Introduction: The aim of the study is to document the knowledge, practices and perceptions of the study population, pertaining to menstruation and also to document the treatment seeking behav- iour of the study participants for menstrual problems ...
Shailee Vyas +2 more
doaj
Keeping up with evidence-based recommendations - a qualitative interview study with general practitioners in Germany on information-seeking behaviour in cardiovascular care. [PDF]
BMC Prim Care, 2023 Arnold C +3 more
europepmc +1 more source
Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source
Studying Academic Lawyers' Information Seeking to Inform the Design of Digital Law Libraries
, 2006 We report findings from the initial phase of our study on legal information seeking, which comprised a series of semi-structured interviews and naturalistic observations of academic law students and staff looking for electronic legal information.
Makri, S, Stephann Makri, Makri, S.
core
Research needs a supportive environment for finding information that considers users' needs, resources, and challenges. To explore this environment, the current thesis aims to understand the affective, cognitive, and physical aspects of business higher ...
Maryam Laeeq (18266647)
core +1 more source
Modeling the Information-Seeking Behavior of Social Scientists: Ellis's Study Revisited [PDF]
, 2003 This paper revises David Ellis's information-seeking behavior model of social scientists, which includes six generic features: starting, chaining, browsing, differentiating, monitoring, and extracting.
Meho, Lokman I., Tibbo, Helen R.
core
Information Research: An International Electronic Journal, 2004 This paper reports the results of two empirical studies which explored the information seeking behaviour of engineering and law students in Ireland. Findings reveal similar patterns in the information seeking behaviour between students studying to become
Gillian Kerins +2 more
doaj
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source